Journal article
Control of cystic echinococcosis in the middle atlas, morocco: Field evaluation of the eg95 vaccine in sheep and cesticide treatment in dogs
F Amarir, A Rhalem, A Sadak, M Raes, M Oukessou, A Saadi, M Bouslikhane, CG Gauci, MW Lightowlers, N Kirschvink, T Marcotty
Plos Neglected Tropical Diseases | Published : 2021
Abstract
Background Cystic echinococcosis (CE) is an important cause of human morbidity and mortality world-wide, particularly in Morocco and other North African countries. Methodology/Principal findings We investigated the potential of three strategies to reduce Echinococcus granulosus trans-mission: (1) 4-monthly treatment of dogs with praziquantel, (2) vaccination of sheep with the EG95 vaccine and (3) a combination of both measures. These measures were implemented during four consecutive years in different areas of the Middle Atlas Mountains in Morocco. The outcome of the interventions was assessed through hydatid cyst (viable and non-viable) counts in liver and lungs using necropsy or in vivo ul..
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Awarded by Institut Agronomique et Vétérinaire Hassan II
Funding Acknowledgements
This study has received funding for the various works carried out in the field, from the Academy of Research and Higher Education (ARES) of Belgium, Namur Research Institut (NARILIS), University of Namur, Belgium, Hassan II Agronomy and Veterinary Institute (IAV), Rabat, Morocco and Australian National Health and Medical Research Council Grant GTN1105448 (MWL). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.